| 貨號(hào) | 147 |
|---|---|
| EINECS編號(hào) | 1015-89-0 |
| 品牌 | boye |
| 用途 | 6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimental autoimmune encephalomyelitis (EAE). It also decreases serum levels of lactate dehydrogenase as well as hepatic lipid peroxidation, oxidative DNA damage, and PARP levels. |
| 外觀 | 電詢 |
| CAS編號(hào) | 1015-89-0 |
| 別名 | 6(5H)-5-氮雜菲酮 |
| 保質(zhì)期 | 36月 |
| 級別 | 工業(yè)級 |
| 英文名稱 | Phenanthridin-6(5H)-one |
| 包裝規(guī)格 | 1kg 5kg 25kg |
| 純度 | 98% |
| 分子式 | C13H9NO |
| 質(zhì)量標(biāo)準(zhǔn) | 企業(yè)標(biāo)準(zhǔn) |
6(5H)-5-氮雜菲酮名稱
中文名 6(5H)-菲啶酮
英文名 phenanthridone
中文別名 6(5H)-5-氮雜菲酮
英文別名 更多
6(5H)-5-氮雜菲酮物理化學(xué)性質(zhì)
密度 1.2±0.1 g/cm3
沸點(diǎn) 274.8±7.0 °C at 760 mmHg
熔點(diǎn) 290-292 °C(lit.)
分子式 C13H9NO
分子量 195.217
閃點(diǎn) 158.7±3.1 °C
質(zhì)量 195.068420
PSA 32.86000
LogP 2.81
蒸汽壓 0.0±0.6 mmHg at 25°C
折射率 1.642
儲(chǔ)存條件
保持容器密封，儲(chǔ)存在陰涼，干燥的地方
穩(wěn)定性
常溫常壓下穩(wěn)定，避免氧化物接觸
